Vos caught and passed Amanda Spratt (Mitchelton-Scott) at the top of the climb after Spratt had been on a solo attack for the last of the five 27km laps.
Vos powered to the finish and won with a three-second gap to Leah Kirchmann (Team Sunweb) who beat Cecilie Uttrup Ludwig (Bigla) in the sprint for second place.
Last year, organisers of the Tour de France, ASO, revealed details of their Women's WorldTour one-day race La Course by Le Tour de France that would be scheduled to take place on July 19 in Pau.
The race shifted away from the route that boasted a mountainous race to Le Grand-Bornand last year to a hilly circuit race that was more suited to the puncheurs of the peloton.
The women raced along a circuit race, held on a version of the 27km time trial course used for stage 13 of the men's Tour de France. They completed five laps of the circuit for a total of 121km.
Get The Leadout Newsletter
The latest race content, interviews, features, reviews and expert buying guides, direct to your inbox!
The route included climbs over the Côte d’Esquillot and Cite de Gelos, making the circuit a challenge but one that suited the one-day Classics specialists.
Listen to the latest Cyclingnews Podcast Women's Edition
La Course by Le Tour de France 2019 - top 10
Swipe to scroll horizontally
#
Rider Name (Country) Team
Result
1
Marianne Vos (Ned) CCC-Liv
3:15:20
2
Leah Kirchmann (Can) Team Sunweb Women
0:00:03
3
Cecilie Uttrup Ludwig (Den) Bigla Pro Cycling Team
Row 2 - Cell 2
4
Lucinda Brand (Ned) Team Sunweb Women
0:00:04
5
Ashleigh Moolman-Pasio (RSA) CCC-Liv
0:00:06
6
Elisa Longo Borghini (Ita) Trek-Segafredo Women
Row 5 - Cell 2
7
Annemiek van Vleuten (Ned) Mitchelton-Scott Women
0:00:07
8
Soraya Paladin (Ita) Ale Cipollini
Row 7 - Cell 2
9
Ane Santesteban Gonzalez (Spa) WNT-Rotor Pro Cycling
Row 8 - Cell 2
10
Anna van der Breggen (Ned) Boels Dolmans Cyclingteam
