Andy Schleck has abandoned Tirreno-Adriatico on the sixth stage from Porto to Sant'Elpidio.
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The RadioShack rider pulled out in the first half of the stage after a ferocious early pace. Schleck has endured a difficult year, battling back from a serious injury sustained last year.
He completed the GP di Camaiore last month, the first time he had finished a race since Liege-Bastogne-Liege last year.