Sagan's best finish in the race came in 2012 when he out-paced Oscar Freire for the final podium spot behind winner Enrico Gasparotto and runner-up Jelle Vanendert, but he hasn't started the Dutch event since 2013.
Sagan will be joined by fellow Paris-Roubaix competitor Marcus Burghardt, with Pascal Ackermann, Cesare Benedetti, Patrick Konrad, Jay McCarthy and Gregor Mühlberger.
Ackermann, the runner-up in the Scheldeprijs and Driedaagse De Panne, will be making his debut in the race.
McCarthy is the top climber in the team's ranks, and showed strong form last week with a stage win in the Vuelta al Pais Vasco.
Bora-Hansgrohe for Amstel Gold Race: Pascal Ackermann, Cesare Benedetti, Marcus Burghardt, Patrick Konrad, Jay McCarthy, Gregor Mühlberger, Peter Sagan