Kruijswijk was supposed to be part of Jumbo-Visma's trio of leaders alongside Primoz Roglic and Tom Dumoulin. However, he will now hope to recover from his injuries and ride the Giro d'Italia in October.
"Unfortunately, the consequences of my crash in the Dauphiné turned out to be more serious than hoped. To my great disappointment, I cannot participate in the Tour de France due to a shoulder fracture and the many abrasions," Kruijswijk said in an announcement from the Jumbo-Visma team.
"I wish the team the best of luck at the Tour, and I am very disappointed that I cannot be part of it."
Kruijswijk will be replaced by Norwegian Amund Grøndahl Jansen, according to reports in the Netherlands, giving the Jumbo-Visma team extra strength on the flat and rolling roads.
"Steven has done everything he could for the past few months and sacrificed everything to start the Tour de France in top shape. But top sport is tough. directeur sportif Merijn Zeeman said.
"It is a great disappointment we cannot continue with our plan. Amund Grøndahl Jansen will replace Steven. Amund is well prepared and will provide maximum support to the team and the team leaders."
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